Publications

Found 52 results
2012
El Gaamouch F, Buisson A, Moustié O, Lemieux M, Labrecque S, Bontempi B, De Koninck P, Nicole O.  2012.  Interaction between αCaMKII and GluN2B controls ERK-dependent plasticity.. J Neurosci. 32(31):10767-79.
Lemieux M, Labrecque S, Tardif C, Labrie-Dion É, Lebel E, De Koninck P.  2012.  Translocation of CaMKII to dendritic microtubules supports the plasticity of local synapses.. J Cell Biol. 198(6):1055-73.
2011
Laffray S, Pagès S, Dufour H, De Koninck P, De Koninck Y, Côté D.  2011.  Adaptive movement compensation for in vivo imaging of fast cellular dynamics within a moving tissue.. PLoS One. 6(5):e19928.
Pagès S, Côté D, De Koninck P.  2011.  Optophysiological approach to resolve neuronal action potentials with high spatial and temporal resolution in cultured neurons.. Front Cell Neurosci. 5:20.
Therrien OD, Aubé B, Pagès S, De Koninck P, Côté D.  2011.  Wide-field multiphoton imaging of cellular dynamics in thick tissue by temporal focusing and patterned illumination.. Biomed Opt Express. 2(3):696-704.
2010
Pi HJae, Otmakhov N, Lemelin D, De Koninck P, Lisman J.  2010.  Autonomous CaMKII can promote either long-term potentiation or long-term depression, depending on the state of T305/T306 phosphorylation.. J Neurosci. 30(26):8704-9.
Pi HJae, Otmakhov N, El Gaamouch F, Lemelin D, De Koninck P, Lisman J.  2010.  CaMKII control of spine size and synaptic strength: role of phosphorylation states and nonenzymatic action.. Proc Natl Acad Sci U S A. 107(32):14437-42.
Opazo P, Labrecque S, Tigaret CM, Frouin A, Wiseman PW, De Koninck P, Choquet D.  2010.  CaMKII triggers the diffusional trapping of surface AMPARs through phosphorylation of stargazin.. Neuron. 67(2):239-52.
Nault F, De Koninck P.  2010.  Dissociated Hippocampal Cultures. Protocols for Neural Cell Culture: Fourth Edition. :137-159.
Parys B, Côté A, Gallo V, De Koninck P, Sík A.  2010.  Intercellular calcium signaling between astrocytes and oligodendrocytes via gap junctions in culture.. Neuroscience. 167(4):1032-43.
2009
Heinze KG, Costantino S, De Koninck P, Wiseman PW.  2009.  Beyond photobleaching, laser illumination unbinds fluorescent proteins.. J Phys Chem B. 113(15):5225-33.
2007
Smith BA, Roy H, De Koninck P, Grütter P, De Koninck Y.  2007.  Dendritic spine viscoelasticity and soft-glassy nature: balancing dynamic remodeling with structural stability.. Biophys J. 92(4):1419-30.
Taylor DM, De Koninck P, Minotti S, Durham HD.  2007.  Manipulation of protein kinases reveals different mechanisms for upregulation of heat shock proteins in motor neurons and non-neuronal cells.. Mol Cell Neurosci. 34(1):20-33.
De Koninck P, Labrecque S, Heyes CD, Wiseman PW.  2007.  Probing synaptic signaling with quantum dots.. HFSP J. 1(1):5-10.
2006
Davidovic L, Tremblay S, Gravel M, De Koninck P, Khandjian EWMiky.  2006.  [The fragile X syndrome: one protein missing and 1001 disoriented mRNAs].. Med Sci (Paris). 22(1):41-6.
Bayer K U, Lebel E, McDonald GL, O'Leary H, Schulman H, De Koninck P.  2006.  Transition from reversible to persistent binding of CaMKII to postsynaptic sites and NR2B.. J Neurosci. 26(4):1164-74.
2005
Thibaud C, Koubassov V, De Koninck P, Chin SL, De Koninck Y.  2005.  Destruction of polymer growth substrates for cell cultures in two-photon microscopy.. J Microsc. 220(Pt 2):120-7.
Hudmon A, Lebel E, Roy H, Sik A, Schulman H, M Waxham N, De Koninck P.  2005.  A mechanism for Ca2+/calmodulin-dependent protein kinase II clustering at synaptic and nonsynaptic sites based on self-association.. J Neurosci. 25(30):6971-83.
Costantino S, Heinze KG, Martínez OE, De Koninck P, Wiseman PW.  2005.  Two-photon fluorescent microlithography for live-cell imaging.. Microsc Res Tech. 68(5):272-6.
2003
Dupont G, Houart G, De Koninck P.  2003.  Sensitivity of CaM kinase II to the frequency of Ca2+ oscillations: a simple model.. Cell Calcium. 34(6):485-97.
Coull JAM, Boudreau D, Bachand K, Prescott SA, Nault F, Sik A, De Koninck P, De Koninck Y.  2003.  Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain.. Nature. 424(6951):938-42.
2002
Bayer K U, De Koninck P, Schulman H.  2002.  Alternative splicing modulates the frequency-dependent response of CaMKII to Ca(2+) oscillations.. EMBO J. 21(14):3590-7.
2001
Bayer K U, De Koninck P, Leonard AS, Hell JW, Schulman H.  2001.  Interaction with the NMDA receptor locks CaMKII in an active conformation.. Nature. 411(6839):801-5.
1998
De Koninck P, Schulman H.  1998.  Sensitivity of CaM kinase II to the frequency of Ca2+ oscillations.. Science. 279(5348):227-30.
1995
Mandelzys A, De Koninck P, Cooper E.  1995.  Agonist and toxin sensitivities of ACh-evoked currents on neurons expressing multiple nicotinic ACh receptor subunits.. J Neurophysiol. 74(3):1212-21.

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Funding

Our research endeavors are made possible by the following agencies:

Canadian Institutes of Health Research - Instituts de recherche en santé du Canada Fonds de recherche du Québec – Nature et technologies (FRQNT)Fonds de la recherche en santé du Québec   Natural Sciences and Engineering Research Council of Canada (NSERC) - Conseil de recherche en sciences naturelles et en génie du Canada (CRSNG)innovation.caHuman Frontier Science ProgramCanada First Research Excellence FundSentinelle Nord